Table of Contents
AICAR Powder Acadesine Sarms Briefing :
AICAR is a cell-permeable adenosine analog that is a selective activator of AMP-activated protein kinase (AMPK) in adipocytes and hepatocytes. The AMPK is a metabolic regulator that inhibits anabolic processes and is active when energy availability is reduced. AICAR is reported to promote osteogenic differentiation of mesenchymal stem cells in vitro and astroglial differentiation in neural stem cells.
Aicar alias: Acadesine
Aicar CAS: 2627-69-2 Aicar purity: 99.8%
Aicar Chemical Properties: white or off-white solid
Aicar Product Categories: Carbohydrates & Derivatives;Nucleotides;Protein Kinase;Cardiovascular
Aicar Usage: Glucose uptake stimulant; AMPK activator; AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) hav e been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
AICAR Specification:
| Item | Specification | Result |
| Appearance | White powder | Complies |
| Related substance (HPLC) | Total impurity ≤0.5% Max single impurity ≤0.1% | 0.2% 0.06% |
| Odor | Characteristic | Complies |
| Assay | 99% | 99.8% |
| Sieve analysis | 100% pass 80 mesh | Complies |
| Loss on Drying Residue on Ignition | ≤1.0% ≤1.0% | 0.12% 0.09% |
| Heavy Metal | <10ppm | Complies |
| As | <0.1ppm | 0.05ppm |
| Pb | <0.1ppm | 0.05ppm |
| Cd | <0.1ppm | 0.05ppm |
| Residual Solvents | <100ppm | Complies |
| Residual Pesticide | Negative | Complies |
| Microbiology | ||
| Total Plate Count | <1000cfu/g | Complies |
| Yeast & Mold | <100cfu/g | Complies |
| E.Coli | Negative | Complies |
| Salmonella | Negative | Complies |
(2). AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
(3). AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion.
(4). With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion.Additionally, the peptide’s presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
AICAR Powder Acadesine Sarms Effects :
AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) hav e been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
Biological Activity Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes.
1) Fat loss
2) AMP-activated Protein Kinase
3) Protect against ischemic Injury
AICAR Powder Acadesine Sarms Dosage:
1) new users:25mg/day
2) Advanced users: those who had already experienced with steroids, peptides or:50mg/day
3) Competitors and Professionals:75mg/day,divide the injections during the day
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