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CJC- 1295 With Dac Powder Briefing
CJC-1295 is a tetrasubstituted 30-amino acid peptide hormone, primarily functioning as a releasing hormone (GHRH) analog.One of the advantages of CJC-1295 over traditional GHRH is its ability to bioconjugate with serum albumin, thus increasing its half-life and therapeutic window. It accomplishes this by using protecting groups around the amino acids of GHRH typically susceptible to enzymatic degradation.
Products Name; CJC 1295
CAS No.: 863288-34-0
Molecular Formula: C165H271N47O46
Molecular Weight: 3649.30
Purity (HPLC): 98.0%
Appearance: White powder
Alias: CJC-1295 Acetate; CJC1295(Without DAC);
Grade:Pharmaceutical Grade
Use: Hormones and Regulation of Endocrine Function of Drug
The principal use of CJC-1295 is to provide increased GH levels, which also results in increased IGF-1 levels. An increase in these levels can aid fat loss and in some instances can aid muscle gain as well. Generally, a product in the GHRH category, including CJC-1295, is chosen as an alternate to using GH, and only rarely is combined with GH.
The other principal GHRH product is Mod GRF 1-29, which in most instances I recommend over CJC-1295. The products differ in their duration of action. Mod GRF has an approximately-ideal short duration of action allowing pulsatile dosing, whereas CJC-1295 has an extended duration of action which prevents such dosing.
It’s important to avoid confusing CJC-1295 with “CJC-1295 w/o DAC.” The latter is not CJC-1295, but rather is misnamed Mod GRF. When a peptide doesn’t have DAC, it’s not CJC-1295.
CJC 1295 is sometimes marketed as “CJC-1295 with DAC.” This simply is CJC-1295.
CJC-1295 Specification
| Product name | CJC-1295 Acetate |
| CAS register number | 863288-34-0 |
| Molecular formula | C165H271N47O46 |
| Molecular weight | 3649.30 |
| Assay | 99% |
| Appearance | White powder |
| Single Impurity(HPLC) | 1.0%max |
| Amino Acid Composition | 10% of theoretical |
| Peptide Content(N%) | 80%(by %N) |
| Water Content(Karl Fischer) | 6.0% |
| Acetate Content(HPIC) | 15.0% |
| MS (ESI) | Consistent |
| Mass Balance | 95.0~105.0% |
| Price | Negotiated |
When to use CJC-1295
This product is most suited to instances where an individual wishes to inject infrequently and is seeking substantive support for GH production rather than a maximum or near-maximum increase. This is because the flat blood levels it provides do not match up well with pulsatile dosing, which is needed for greatest effect. The steady levels can provide very good support for natural GH pulses, however.
Relatively rarely, adverse side effects associated with excessive GH use, such as pain from nerve compression (such as carpal tunnel pain), excessive water retention, or reduced insulin sensitivity can occur from CJC-1295 use. The cause is stimulation of a greater amount of GH production than is suitable for the individual case. The solution is to discontinue use until the problem is resolved, and to reduce dosage when resuming use.
For ongoing support of GH production, at doses recommended below, CJC-1295 does not need to be cycled.
How to use CJC-1295
CJC 1295 is typically provided in vials containing 2 or 5 mg of lyophylized powder, though the amount can vary. The contents should be reconstituted by adding a convenient amount of sterile or bacteriostatic water. If for example 2 mL is chosen and the dosing of the vial is 2 mg, the resulting solution then has a concentration of 1 mg/mL, or 1000 mcg/mL.
At time of dosing, an insulin syringe is used to draw and then inject the desired amount. In the above example, a 1000 mcg dose would require a volume of 1 mL, or “100 IU” as marked on an insulin syringe.
Injection may be subcutaneous, intramuscular, or intravenous according to personal preference. If desired, peptide solutions from other vials, such as a vial of a GHRP product, may also be drawn into the same syringe, if there is room. This reduces the total number of injections required.
When recommending CJC 1295, I ordinarily recommend a dosage of 1000 mcg at a time, twice per week.
CJC-1295 DAC vs. CJC-1295 No DAC
CJC-1295 DAC and CJC-1295 (also known as Modified GRF 1-29) are Releasing Hormones (GHRH). Their action in the human body is identical but the difference between the two peptides are the span of the half-life. Modified GRF 1-29 and Sermorelin have a very short acting half-life of about 30 minutes, while CJC-1295 DAC has a half-life that can last up to approximately 8 days. Many a scientist have reported that the short half-life of Sermorelin and Modified GRF 1-29 is considered to be much more natural.
CJC-1295 Advantages
1. Supports GH secretion 2-10 times!
2. Half-life of 7 days
3. Simple application twice a week
4. Improving sleep
5. The rejuvenation of joints, tendons and ligaments
6. Faster recovery
7. Muscle growth
8. Reducing the amount of subcutaneous fat
CJC-1295 Dosage Tips:
The available literature indicates dose of 1000 mcg administered every three days (twice a week).The recommended duration of use is two months to half a year. Best results are obtained by combining the product GHRP-6CJC-1295 is suitable in combination with AS (anabolic steroids) in volume and pre-competition period, as well as to the PCT (Post Cycle Therapy).
CJC-1295 Usage :Using once a day before sleep, each vial will last 13 days. Taken twice a day (morning and night) for body building, the vial will last a week.
Combining CJC1295 with GHRP-2 or GHRP-6, will produce a larger and more sustained GH release.
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