What is Clomid Powder?
Clomid Powder is a non-steroidal fertility medicine. It causes the pituitary gland to release hormones needed to stimulate ovulation (the release of an egg from the ovary).
Clomid Powder is used to cause ovulation in women with certain medical conditions (such as polycystic ovary syndrome) that prevent naturally occurring ovulation.
Clomid may also be used for purposes not listed in this medication guide.
Clomid Powder Description
Clomid Powder is the anti-estrogen of choice for improving recovery of natural testosterone production after a cycle, improving testosterone production of endurance athletes, and is also effective in reducing risk of gynecomastia during a cycle employing aromatizable steroids. While it has been claimed that Clomid “stimulates” production of luteinizing hormone (LH) and therefore of testosterone, in fact Clomid’s activity is achieved not by stimulation of the hypothalamus and pituitary, but by blocking their inhibition by estrogen. Clomid is a mixed estrogen agonist/antagonist (activator/blocker) which, when bound to the estrogen receptor, puts it in a somewhat different conformation (shape) than does estradiol. The estrogen receptor requires binding of an estrogen or drug at its binding site and also the binding of any of several cofactors at different sites. Without the binding of the cofactor, the estrogen receptor is inactive. Different tissues use different cofactors. Some of these cofactors are able to bind to the estrogen receptor/Clomid complex, but others are blocked due to the change in shape. The result is that in some tissues Clomid acts as an antagonist — the cofactor used in that tissue cannot bind and so the receptor remains inactive — and in others Clomid acts as an agonist (activator), because the cofactors used in that tissue are able to bind.
Model NO.: Clomid Powder
Suitable for: Adult
Purity: >99%
Name: Clomid
Clomid MW: 528.53
Clomid HS Code: 9602001000
Clomiphene Citrate/Clomid powders/CAS No: 50-41-9
Clomid Model No: 50-41-9
Clomid Mf: C32h36clno8
Clomiphene Citrate Powder Half Life: Active half-life 5-7 hrs
Clomiphene Citrate Powder Dosage: 50 mg daily
Clomiphene Citrate Powder Detection time: 2 months
Clomiphene Citrate Powder side Effect: Hoarseness,ankle swelling acne,vomiting,nausea,more hair on the face changes in menstrual periods,changes in skin color
Clomiphene Citrate Powder Results: Weight loss and muscle growth for bodybuilder and athletes
Background
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Indication
Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
How Does Clomid Powder Work?
In short, taking Clomid Powder prompts your body to release hormones that increase the chances of your ovaries releasing a mature and ready-to-be-fertilized egg. Some patients take Clomid as part of fertility treatment, such as an IUI (intrauterine insemination) or IVF (in vitro fertilization) cycle, but many start simply by taking Clomid and having sex.
The idea is to “try to increase the odds of sperm and egg meeting,” says Kenan Omurtag, M.D., division director of the reproductive endocrinology and infertility department at the Washington University School of Medicine in St. Louis.
Clomid Powder works by binding to the receptors in your brain that would typically bind with estrogen. As a result, your brain thinks your estrogen levels are low and compensates by producing more FSH, or follicle-stimulating hormone, which can boost estrogen. FSH’s primary function is fertility-related—as the name implies, the hormone stimulates your ovarian follicles, encouraging them to grow. An ovarian follicle is a tiny fluid sac in your ovaries that holds an immature egg, called an oocyte. Most women are born with a reserve of millions of oocytes that gradually depletes throughout a lifetime.
By triggering follicle growth, FSH helps oocytes grow into mature eggs. Ideally, while on Clomid, at least one of those eggs will mature enough to release from the follicle and be swept into the fallopian tubes, where it can meet with sperm to be fertilized into an embryo.
Who Should Take Clomid Powder?
If you have been trying to get pregnant through sex for at least a year (or for six months if you’re older than 34), you may be a candidate for Clomid. Clomid is often prescribed for patients with:
- Unexplained infertility. It can be frustrating to hear that there isn’t a clear explanation for your inability to get pregnant. However, you’ll likely receive this diagnosis if you have regular menstrual cycles and at least one working fallopian tube, and your partner’s sperm tests don’t reveal any problems with count or motility. Up to 30% of couples seeking fertility treatment are diagnosed with unexplained fertility. Since there’s no identified problem to target, your doctor will likely prescribe an oral medication like Clomid because it’s non-invasive and relatively inexpensive compared to other fertility treatments.
- Irregular menstrual cycles. If you don’t ovulate on a typical monthly schedule or don’t ovulate at all, your doctor may prescribe Clomid to help induce ovulation.
- Polycystic ovary syndrome (PCOS). Patients with PCOS often experience either infrequent periods or no periods at all and may be prescribed Clomid. However, U.S. guidelines now recommend letrozole, another oral medication, as the first-line fertility treatment for women with anovulatory (which refers to the absence of ovulation) PCOS who are trying to conceive, as success rates in recent studies have been slightly higher with letrozole versus clomiphene citrate.
When and How to Take Clomid Powder?
Clomid Powder comes in 50-milligram tablets. The most common starting dose is one tablet a day for five days, beginning on the third, fourth or fifth day of your menstrual cycle. From there (unless you’re using Clomid with a IUI or IVF cycle), you need to have sex timed to your fertile window, which is the six-or-so-day time period during your menstrual cycle that you’re able to get pregnant.
If you don’t get pregnant during your first month of taking Clomid, your doctor may increase your dose to two or three tablets a day during your next menstrual cycle. Never take Clomid without a prescription.
Clomid Side Effects and Dosages
Side effects reported by users are limited, but the sides that do appear tend to be directly correlated to high dosages of the drug. In my experience, a dose of 50-100 mgs per day is enough to do the job. In fact, studies have shown a 150mg per day dosage of clomiphene citrate can increase testosterone levels by 150%. I have read some users going as high as 200mg or even 300mg a day. I believe this is not necessary based on my own blood work.
When used at higher dosages, over 200mgs per day, side effects may include feeling depressed or ‘bitchy’; anecdotally, some users report feeling very emotional (think PMS). When used at a proper dose and when stacked with PCT aids such as: HCGenerate, Cardarine (GW) and N2Guard, the user will rarely have any side effects. Many users experience a spike in libido, ejaculation volume, and well being during this period when clomid is used properly.
Bottom line is, clomid is a great option for post cycle therapy. If used properly, users will report very little side effects and many benefits.
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