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Dexamethasone Powder CAS:50-02-2

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CAS:50-02-2
Standard:USP34
MF:C22H29FO5
MW:392.47
EINECS:200-003-9
Properties
Melting point:262-264 °C (lit.)
alpha 75 º (c=1, dioxane)
Boiling point:568.2±50.0 °C(Predicted)
Density 1.1283 (estimate)
refractive index 76 ° (C=1, Dioxane)
Flash point:9℃
storage temp. 2-8°C
solubility ethanol: 1 mg/mL
form powder
pka12.13±0.70(Predicted)
color off-white
Water Solubility 10 mg/100 mL (25 ºC)
Sensitive Light Sensitive
Merck 14,2943
BRN 2066651
BCS Class1 (CLogP), 3 (LogP)
Stability:Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. May be light sensitive.

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Table of Contents

Dexamethasone Powder Briefing

powder, BioReagent, suitable for cell culture, ≥99%

Dexamethasone Powder, a synthetic adrenocortical steroid, is a white to practically white, odorless, crystalline powder. It is stable in air. It is practically insoluble in water. The molecular formula is C22H29FO5. The molecular weight is 392.47. It is designated chemically as 9-fluoro-11β, 17, 21-trihydroxy-16α-methylpregna-1, 4-diene, 3, 20-dione and the structural formula is:

Dexamethasone Powder 

Synonym(s):
(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F
Empirical Formula (Hill Notation):

Dexamethasone Powder is a corticosteroid that prevents the release of substances in the body that cause inflammation.

Dexamethasone Powder is used to treat many different inflammatory conditions such as allergic disorders and skin conditions.

Dexamethasone Powder is a corticosteroid indicated for allergic states, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematologic disorders, neoplastic diseases, nervous system, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders. Dexamethasone is available as a generic.

Dexamethasone Powder COA

DEXAMETHASONE powder COA

Dexamethasone Powder Benefits and side effects

Dexamethasone Powder provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, arthritis, asthma, blood or bone marrow problems, kidney problems, skin conditions, and flare-ups of multiple sclerosis. Dexamethasone is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.

Dexamethasone tablets are also used in combination with other anti-myeloma products for the treatment of adults with multiple myeloma.

This medicine is available only with your doctor’s prescription.

This product is available in the following dosage forms:

  • Tablet
  • Elixir
  • Solution

What Are Side Effects of Dexamethasone?

Side effects of dexamethasone include: vision changes, swelling, rapid weight gain, sleep problems (insomnia), mood changes, acne, dry skin, thinning skin, bruising or discoloration, slow wound healing, increased sweating, headache, dizziness, spinning sensation, nausea, stomach pain, bloating, muscle weakness, or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist). Rare instances of severe allergic reactions (anaphylaxis) have occurred in patients receiving corticosteroid therapy such as dexamethasone.

Dosage for Dexamethasone Powder

Dexamethasone Tablets are available in 0.5, 0.75, 1, 1.5, 2, 4 and 6 mg strengths. The initial dosage for Dexamethasone varies from .75 to 9 mg a day depending on the disease being treated.

Dexamethasone During Pregnancy and Breastfeeding

Infants born to mothers who have received substantial doses of corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism. Because of the potential for serious adverse reactions in nursing infants from corticosteroids, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Use in pediatric patients is recommended to be done in consultation with a pediatric specialist.

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