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Dimethocaine Powder Briefing
Dimethocaine which is also known as DMC, larocaine, is considered as an anesthetic that, on account of its closeness in real life to cocaine, has potential for misuse. Dimethocaine is a compound that has a stimulatory effect. This compound totally restrains dopamine uptake in rats striatal synaptosomes with an IC50 worth of 1.2 µM tantamount to that of cocaine (IC50 = 0.7 µM) accordingly, dimethocaine portion conditionally fill in for cocaine in drug separation tests in rats and rhesus monkeys
Dimethocaine is a 4-aminobenzoic acid that resembles the active substance of procaine. It is commonly used as a white powder. It was originally developed by the Hoffmann-La Roche Company in 1930 as a local anesthetic. During the 1930s, dimethocaine was commonly used in the US as a local anesthesia for cosmetic surgery and other procedures. However, it was discontinued during the 1940s due to its psychoactive effects.
Portions of cocaine and other local anesthetics such as dimethocaine can inhibit the uptake of dopamine by blocking the dopamine transporters. This impairs the movement and cognition of the neurotransmitter.
Due to the properties of drugs such as dimethocaine, which are known to inhibit the central nervous system’s dopamine uptake, they can create a euphoric effect. In vitro and in vivo measurements of the activity of dimethocaine in the dopaminergic reuptake inhibitor paradigm revealed its potent and effective effects.
However, dimethocaine is considered in some countries as a legal cocaine replacement and is even listed by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) under the category “synthetic cocaine derivatives”
The toxicological and physiological properties of this compound has not been analyzed. Usage of this Chemical should be for research and forensic purposes only.
Dimethocaine Powder COA
Dimethocaine Powder for sale/ Buy Dimethocaine powder
1.)Dimethocaine is a new local anesthetic that is similar to cocaine and can cause a similar effect. Dimethocaine completely inhibits the absorption of dopamine in the synapse of the rat penis with an IC50 of 1.2 μM, comparable to that of cocaine (IC50 = 0.7 μM). As a result of Dimethocaine, depending on the amount of dosage, replaces cocaine. Dimethocaine is intended for judicial and research purposes.
There are user reports that confirm unpleasant effects on the heart. Dimethocaine (DMC, larocaine), a synthetic derivative of cocaine. It is a widely distribute “legal high” consume as a “new psychoactive substance” (NPS). Also originally in the 1930s as an anesthetic, primarily in dentistry, ophthalmology, and otolaryngology. Moreover, This drug completely inhibits dopamine transporter and have the potential for abuse. Dimethocaine is use for forensic and research purposes.
2.)Buy Dimethocaine powder . Dimethocaine, also known as DMC or larocaine, is a compound with a stimulatory effect. This effect resembles that of cocaine, although dimethocaine appears to be less potent. However, Just like cocaine, dimethocaine is addictive due to its stimulation of the reward pathway in the brain. More so, dimethocaine is a legal cocaine replacement in some countries. Also, it is list by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). Under the category “synthetic cocaine derivatives”. The structure of dimethocaine, being a benzoic ester acid, resembles that of procaine. It is a white powder at room temperature.
Cocaine and other local anesthetics are known to produce cardiotoxicity by blocking sodium channels. However, no reports are publish of these same effects of cardiotoxicity associated with dimethocaine. However, There is little research about toxicity of dimethocaine in humans Therefore the exact lethal or pharmacological doses are unknown.
Dimethocaine is often abuse as a legal substitute for cocaine. The drug is administer intravenously or nasally, because ingestion would lead to rapid hydrolyzation. More so, It’s positive effects are euphoria, stimulation, increase talkativeness and mood lift. However, because the drug acts similar as cocaine, it has comparable negative side effects. These side effects include: tachycardia, difficulty with breathing, pain on the chest. Also, vasoconstriction, insomnia, aranoia and anxiety. Dimethocaine probably poses larger health issues than cocaine. This is due to the fact that more dimethocaine is administer to produce the same euphoric feeling. This resulting in larger risk for the negative effects. Buy Dimethocaine powder
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