Guanidine thiocyanate Briefing
Guanidine Thiocyanate is a strong chaotropic protein denaturant, and is intended for use in isolation of nucleic acid.Guanidine Thiocyanate is an ultrapure, molecular biology grade reagent. It is free of detectable nuclease and protease activity and is a strong protein denaturant, as both the guanidinium cation and the thiocyanate anion are chaotropic agents. It is provided in one bottle containing 500 g. It is recommended for isolation of RNA, especially for tissues such as pancreas with high levels of RNase activity. In solution, it is known as guanidinium thiocyanate. Guanidine Thiocyanate is thoroughly tested for contaminating nonspecific endonuclease, exonuclease, and RNase activity.
Guanidine thiocyanate can be used as biochemical reagent and pharmaceutical intermediate. It is used for degreasing in oil industry, as a strong fat degrading agent in daily chemical industry and as a cell membrane rupture agent in biopharmaceutical industry.
Chemical Name: Guanidine thiocyanate
CAS No.:593-84-0
Molecular Formula:CH5N3.CHNS
Molecular weight: 118.16
Appearance: White crystal
SPECIFICATION:
| Appearance | WHICH CRYSTALS |
| Assay | 99.5% MIN |
| Solubility | CLEAR AND HAZE FREE |
| Water | 0.50% MAX |
| Melting Point | 118-121ºC |
| Absorbance(280nm) 3m In Water | 0.60% MAX |
| Absorbance(300nm) | 0.20MAX |
| PH(11.8% In Water) | 5.0-7.0 |
| Ash | 0.50%MAX |
| Cd | 5mg/kg MAX |
| Co | 5mg/kg MAX |
| Cr | 5mg/kg MAX |
| Cu | 5mg/kg MAX |
| Fe | 5mg/kg MAX |
Application of Guanidine thiocyanate
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