Table of Contents
Letrazole /Femara Powder Briefing:
Reduce estrogen levels: Letrozole (Femara) also does quite a few things which would be of interest to both bodybuilders and athletes.Firstly, it has been shown to reduce estrogen levels by 98% or greater.
Letrozole (Femara) reduced estrogen in the test subject to undetectable levels, and increased LH, FSH and SHBG.Clearly this is all of interest to bodybuilders, as less estrogen in the body means less chance of certain side effects such as water-retention, Gynocomastia, and acne.This makes Letrozole (Femara) an appropriate choice for even the heaviest bulking or cutting cycles including harsh androgens.
Breast Cancer: Letrozole (Femara) was developed to fight breast cancer by inhibiting the aromatization.
Increase LH and FSH: Letrozole (Femara) can be used to raise LH and FSH (which are hormones which signal your testes to produce more testosterone).It will raise your testosterone levels via this mechanism. Again, this is of interest to athletes and bodybuilders for obvious reasons.
Product name: Letrazole,Femara
Synonyms: 4,4′-(1h-1,2,4-Triazol-1-Ylmethylene)Bisbenzonitrile; Lelrozol; 4,4′-(1h-1,2,4-Triazol-1-Ylmethylene) Bis-Benzonitrile;Letrozol; Femara
CAS: 112809-51-5
Molecular Formula: C17H11N5
Molecular Weight : 285.31
Melting point: 181-183oC
Appearance: Off-white crystalline powder
Assay: 99.5%
Usage: femara is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testoster levels because of the lowered estrogen in the body.
Letrazole/Femara Powder Application:
For pre-contest bodybuilders, Femara is almost a necessity to eliminate water retention and achieve the ripped look necessary to compete in today’s bodybuilding world. However, in my experience, it is only necessary to be used for the last 4-6 weeks, to eliminate excess estrogen and water retention. After using Femara I recommend staying away from any estrogen suppression for at least a month to try to normalize the body.
Femara is a type II (non-steroidal) third generation aromatase inhibitor. Clinically it is used to treat postmenopausal women with either estrogen receptor positive or estrogen receptor unknown breast cancer. In women with breast cancer, it has been shown to reduce estrogen levels by 98% or more .
However, it’s use and benefits are not limited to eliminating estrogen in women.
Effects of Letrozole:
Letrozole as an anti-estrogen is extremely beneficial to breast cancer patients. Many forms of breast cancer actively feed off the estrogen hormone. By inhibiting the production of estrogen, which in turn lowers the amount of circulating estrogen in the body, this has the ability to starve the cancer. For years Nolvadex was the preferred form of treatment for this purpose. Nolvadex actively binds to the estrogen receptor, thereby preventing estrogen from binding. However, it does not inhibit or lower production. Nolvadex is still extremely valuable in breast cancer treatment plans, but many physicians, especially in extreme cases have begun to use AI’s first. Once the cancer is in remission, at this stage a SERM like Nolvadex may replace the AI in an effort to protect against the cancer reappearing.
Undeniably, AI’s like Letrozole are the most effect means at combating estrogenic related side effects. However, they can also have a negative impact on cholesterol. Alone AI’s do not appear to have a strong, negative effect on cholesterol, but when coupled with an aromatizing steroid like testosterone the adverse cholesterol effect is enhanced. For this reason, many will find SERM’s like Tamoxifen Citrate (Nolvadex) should be their first choice in estrogen protection. SERM’s will not negatively affect cholesterol; in fact, SERM’s, while anti-estrogenic, actively act as estrogens in the liver, and in turn, promote healthier cholesterol levels. We’ll look at this in more detail in the side effect section, and while Letrozole can be used without an adverse cholesterol effect, it will take some effort on your part.
Femara and Letrozole Dosing:
The most common dose of Femara is 2.5 mg per day on days five through nine of the menstrual cycleSometimes it is given in higher doses of 5 mg or 7.5 mg per day.
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