Table of Contents
Avanafil Powder Briefing:
Avanafil is a phosphodiesterase type 5 (PDE5) inhibitor. It works by helping to increase blood flow into the penis during sexual stimulation. This helps you to achieve and maintain an erection.
Avanafil is used for the treatment of impotence (erectile dysfunction).
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2014, and by EMA on June 21, 2015. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are tadalafil and vardenafil. The advantage of avanafil is that it has the very fast onset of action compared with other PDE5 inhibitors.It is absorbed quickly. reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.
Avanafil Assay: 99% min.
Avanafil CAS: 330784-47-9
Avanafil Molecular Formula: C23H26ClN7O3
Avanafil Molecular Weight:483.9506
Avanafil Character: White to Off-WhiteCyrstalline Solid.
Avanafil Specification:
| Product Name | Avanafil | ||
| CAS NO | 330784-47-9 | Outer packing | 1KG/BAG |
| Product Date | July, 2017 | Shelf Life | Jun, 2018 |
| Standard Adopted | IHS | ||
| Item | Specification | Result | |
| Description | a white or off white crystalline powder | a white crystalline powder | |
| Solubility | soluble in dimethyl sulfoxide & slightly soluble in ethanol and methanol | Complies | |
| Identification,HPLC | the principal peak in the chromatogram obtained with test solution is corresponds to retention time the principal peak in the chromatogram obtained with RS in the assay | Complies | |
| Melting point | 132-165ºC | 163ºC | |
| Heavy Metals | not more than 10ppm | Complies | |
| Loss on drying | not more than 0.5% | 0.248% | |
| Specific optical rotation | -18.0 °to -26.0° | -25.06° | |
| Residual solvent | |||
| Methanol | NMT 3000ppm | Complies | |
| Sulphated ash | not more than 0.1% | 0.05% | |
| Assay | 98-102% on dry basis | 99.811% | |
| Conclusion | Qualified | ||
Avanafil Powder Dosage:
It is available in 2.5 mg, 5 mg, 10 mg, and 20 mg doses in round orange tablets. The normal starting dose is 10 mg.
Vardenafil should be taken 1 to 2 hours prior to sexual activity, with a maximum dose frequency of once per day.
How to process the order?
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- we quote and confirm your request details
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