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MT2 (Melanotan-II) powder (121062-08-6) Description
Melanotan II (MT-2) is a synthetic peptide, the analogue of a natural hormone that enhances the melanocortin tan (the production of melanin through melanocytes, which determines and makes it possible to tan), thus reducing the risk of sun damage and other harmful effects of solar radiation and solarium.
This peptide MT-2 is a designed to highly stimulate the body’s response to uv ray exposure, because melanin production is supercharged minimum sun exposure is required to gain maximum tanning effect. This is ideal solution for those with fair skin to get tanned without having to spend weeks in the sun and going through the burn and heal process.
MT2 users experience much quicker tanning and faster healing of sun damaged skin cells. Because of this, melanotan II it is especially suited to those who’s skin is pale (skin type 1 & 2) and are prone to burning in the sun.
As for Melanotan II dosage，the standard reception procedure implies taking a single dose of Melanotan II injection in the amount of 1 mg (exact calculation per kilogram is not required, as the doses vary widely), start with 250mkg a day and within 4 days add another 250mkg gradually. On the fourth day increase the dose up to 1mg and stick to this level until the desired tan is achieved. More details about buy Melanotan II (MT-2) online, please do not hesitate to talk with us-peptide supplier.
The Development of Melanotan 2
The initial creation of the synthetic Melanotan 2 peptide can be credited to the University of Arizona. During the course of research aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy. However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1 and Melanotan 2, which exhibit similar effects whilst possessing an extended half-life for functional therapeutic utilization.
α-Melanocyte-Stimulating Hormone Analogues (Melanotan Peptides)
α-Melanocyte-stimulating hormone (α-MSH) is a naturally occurring endogenous melanotan peptide hormone of the melanocortin family, which is considered to be the most important of the melanocyte-stimulating hormones when it comes to stimulating melanogenesis, a process which in mammals is responsible for hair and skin pigmentation. α-MSH also plays a role in feeding behavior, energy homeostasis, and sexual activity (Bremelanotide and Melanotan 2). α-MSH is a nonselective agonist of melanocortin receptors MC1, MC3, MC4 and MC5. Melanotan 1 and Melanotan 2 activate the MC1 receptor, which is responsible for effects on skin pigmentation. Melanotan 2 and PT-141 both stimulate the MC3 and MC4 receptors which are responsible for the regulation of appetite, metabolism, and sexual behavior. However, PT-141 Bremelanotide does not stimulate the MC1 receptor.
A few synthetic analogues of α-MSH have been investigated for their apparent photoprotective effects against ultraviolet (UV) radiation from the sun, namely Melanotan (afamelanotide) and Melanotan II, referred to as Melanotan 2. Bremelanotide, another analogue of α-MSH similar to Melanotan 2, is currently under development for the treatment of sexual dysfunction. All of these melanotan peptides have significantly greater potencies than α-MSH, but with distinctive selectivity peptide profiles.
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