Melanotan2 powder -MT2

CAS Number 121062-08-6
InChIKey JDKLPDJLXHXHNV-MFVUMRCOSA-N
Molecular Formula C50H69N15O9
Molecular Weight 1024.198 g/mol
Monoisotopic Mass 1023.54 g/mol
Melting Point  >181°C (subl.)
Freezing Point ≥17.0
Biological Half-Life 33 hour
Color White
Solubility  Soluble in DMSO
Storage Temperature   –20 °C

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Table of Contents

Melanotan2 powder -MT2 Powder Briefing

Melanotan 2 (also referred to as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis, a process responsible for pigmentation of the skin. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

Additionally, Melanotan 2 and a similar synthetically produced variant, known as PT-141, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.

Product NameRaw MT2 (Melanotan-II) powder
Chemical Name

Melanotan II; MelanotanII;

(3S,6S,9R,12S,15S,23S)-12-((1H-imidazol-5-yl)methyl)-3-((1H-indol-3-yl)methyl)-15-((S)-2-acetamidohexanamido)-9-benzyl-6-(3-guanidinopropyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide

SequenceAc-Nle-cyclo(Asp-His-DPhe-Arg-Trp-Lys)-NH2
ApplicationMelanotan II acetate salt has been used to study its inhibitory effects on feeding and energy expenditure in rats.

 

Melanotan II Acetic Acid Salt, is a lab-made chemical that is similar to a hormone found in people. Melanotan II has been shown to have melanogenesis (tanning) and aphrodisiac effects on humans.

Buying Melanotan 2 MT2 Powder Staying Sun Kissed All Year Round

Don’t be surprised.  A lot of people haven’t heard of Melanotan.  Melanotan is a tanning peptide that stimulates the production of melanin in the body to foster a deep, natural tan.  This is the body’s way of protecting itself from too much sun exposure by increasing the level of melanin in the body.  Melanin is your body’s natural response to UV damage.  The end result is a darkening of the skin.

Obviously, the drawback from too much tanning is the amount of damage UV radiation can do.  This can lead to skin cancer and other serious health problems.

How does MT2 Powder work?

Melanotan 2 works by stimulating the release of the pigment melanin from the skin. Less UV exposure is necessary with Melanotan 2 compared to “normal tanning”, and the tan that occurs with tanning injections is deeper and longer lasting than an individual’s “normal tan”. Melanotan works best (has the most noticeable effects) on people with fair skin tones.

MT2 Benefits:

Lasting Tan:  Even if the dosage is stopped, a warm sun-kissed tan can last for months at a time without any exposure to the sun.  Conversely, tans developed naturally fade in around a months time.

Flexibility of Use:  Able to take a small loading dose with continued dosing until desired skin pigmentation is achieved.  Once achieved only need to dose once every couple of weeks to maintain the same pigment.  

Reduced exposure to sunlight (UV rays):  Melanotan still needs exposure to sunlight to be effective.  However, it will allow the user a significant reduction in time to develop the desired tan.

Side effects:  Side effects for Melanotan 2 include nausea, appetite loss, facial flushing and increased libido. Side effects are generally mild and tend to diminish over time. Some research suggests nausea can be reduced by injecting MT-II after dinner or before bed. Athletes and bodybuilders have injected peptides like Melanotan 2 intermittently to prolong their tan since a tan aided by Melanotan can last 2-3 times as long as a normal tan. Like other peptides, Melanotan is a fragile molecule, therefore Melanotan nasal sprays, pre-mixed peptides, pills, oral and loose powder are not often legitimate for research effectiveness.

Dosage:  Please refer to walk through you will receive after placing your order

.25mg Common Standard

How is MT2 Used?

The peptide is shipped enclosed in a vial.   It is in a powder dried form that must be reconstituted using sterile water and then injected under the skin (subcutaneously) where it is absorbed into the skin and spread throughout.  

The Development of Melanotan 2

The initial creation of the synthetic Melanotan 2 peptide can be credited to the University of Arizona. During the course of research aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy. However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1 and Melanotan 2, which exhibit similar effects whilst possessing an extended half-life for functional therapeutic utilization.

Melanotan 2 Studies and Further Information

Melanotan and Melanotan 2 are both analogs of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan 2 is a cyclic heptapeptide analog of the alpha-melanocyte stimulating hormone (a-MSH).

The effects of Melanotan 2 on the diet and food intake of the laboratory mice have also been investigated. It has been demonstrated that the central melanocortin (MC) has been activated by melanotan 2 when fed and induced in the mice. The six-day treatment of Melanotan 2 has shown that the peptide actually reduced the body weight and the adipose tissue in the viscera of the mice and suppressed the caloric intake of the organism. This has implications in clinical applications of the possible treatment to reduce carbohydrate or calorie intake especially for the overweight and the obese. Furthermore, the same study has also demonstrated that there was a sustained increase in the available oxygen consumption in obese animals. Melanotan 2 also helped reduced the level of serum insulin and the cholesterol levels when compared with the control treatments. Furthermore, it has been suggested that melanotan 2 actually lowers the level of acetylcholine A caboxylase expression and even prevented the reduction of carnitine and palmitoltransferase I mRNA in muscle-type tissues by pair-feeding in the muscles of the obese rats. Moreover, the Melanotan 2 peptide actually increased the fat catabolism in the muscles and even improved the cholesterol metabolism.

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