Melanotan 1 /MT-1 CAS 75921-69-6

MT-I (or Melanotan I, or Afamelanotide, or CUV-1647) is a synthetic analog of peptides nature of endogenous melanocortin peptide alpha-melanocyte stimulating hormone. It has hormones nature as well as common proteins features, its molecular weight/mass is 1646.88 and its molecular formula is C78H111N21O19.

Afamelanotide was specifically developed by American scientists LED by V . Hruby in 1991 as a possible research compound that can be used against skin cancer by stimulating tanning system which in own turn would generate protective natural tan during melanogenesis.

So that synthetic analog was created to determine if it can show the same effect and stimulate melanocytes to produce and release melanin to protect skin from UV. Most of studies and trials were conducted in United States and Australia.

Developed research compound is quite stable cyclic form of original hormone but specifically has much longer half-life period. It works as agonist of specific melanocortin receptor and possesses such property as being selective and thus it promotes increased level of eumelanin above usual pheomelanin, which provides higher efficacy of photoprotection abilities.

COA