Retatrutide vials Briefing
What is Retatrutide ?
Retatrutide is the newest GLP-1R agonist and was approved by the FDA as a once-weekly injection for the treatment of T2DM in late 2017. The peptide is chemically similar to semaglutide,tirzepatide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans.
BENEFITS OF GLP-1 AGONISTS
- Helps slow food leaving your stomach
- Helps prevent your liver from making too much sugar
- Helps the pancreas produce more insul when your blood sugar levels are high
- Can help control blood glucose
- Can reduce hyperglycemia, especially after meals
- Can reduce fasting insul and fasting glucose
- Can reduce hemoglobin A1c
- Can decrease appetite and caloric intake, while inhibiting weight gain
- Has been shown to lower triglyceride levels and oxidative stress from high LDL
- Has been shown to help induce weight loss in obese patients with higher dosing
- Helps decrease leptin and increase leptin sensitivity
- Can increase the conversion of white fat to brown fat
Retatrutide ralated products
| Product No. | Product | Price |
| 1000042820 | Semaglutide 5mg | |
| 1000042821 | Semaglutide 10mg | |
| 1000042822 | Semaglutide 15mg | |
| 1000042823 | Semaglutide 20mg | |
| 1000042824 | Semaglutide Cartridges 5mg*10 | |
| 1000042825 | Semaglutide Cartridges 10mg*10 | |
| 1000042826 | Semaglutide + VitB12 1000mcg/mL | |
| 1000042827 | Semaglutide + VitB6 | |
| 1000042828 | Semaglutide/NAD+ | |
| 1000042829 | Tirzepatide 10mg | |
| 1000042830 | Tirzepatide 15mg | |
| 1000042831 | Tirzepatide 20mg | |
| 1000042832 | Tirzepatide 30mg | |
| 1000042833 | Tirzepatide + VitB12 | |
| 1000042834 | Tirzepatide Cartridges 10-30mg | |
| 1000042835 | Retatrutide 8mg | |
| 1000042836 | Retatrutide 10mg | |
| 1000042837 | Retatrutide 12mg | |
| 1000042838 | NAD+ 500mg | |
| 1000042839 | NAD+ 750mg | |
| 1000042840 | NAD+ 1000mg | |
| 1000042841 | Glutathione 600mg | |
| 1000042842 | GHK-Cu (Copper Peptide) 100mg |
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