Seripiprant Powder Briefing
| cas | 866460-33-5 |
|---|---|
| Name | Seripiprant |
| Appearance | White powder |
| Purity | 99% |
| Delivery Time | 12-15days |
Setipiprant is an orally available, selective CRTH2 antagonist. CRTH2 is a G protein-coupled receptor for PGD2.IC50 value: 6.0 nMTarget: PGD2in vitro: Setipiprant is an orally available, selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T helper [Th]-2 cells) antagonist. CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in various inflammatory diseases, including allergy and asthma. Binding of Setipiprant is a naphthalenecarboxamide.|Setipiprant has been investigated for the treatment of Seasonal Allergic Rhinitis.
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