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Tetracaine HCl Powder Briefing
Tetracaine HCL Powder is a calcium channel protein inhibitor.
Tetracaine HCL Powder is also known as ropivacaine hydrochloride, pantocaine, pantocaine and four ropivacaine hydrochloride. It is easily soluble in water and ethanol, but insoluble in ether, benzene. Tetracaine hydrochloride is a local anesthetic with long-acting ester. In addition, procaine is widely used in clinical, but because of its poor permeability and poor narcotic performance, a small tetracaine was found in 1930 found.
Product Name:Tetracaine HCl Powder
Alias: Tetracaine hydrochloride ,2-Dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride; Amethocaine hydrochloride
CAS NO.: 136-47-0
EINECS: 205-248-5
Assay: 99%+
Grade: Pharmaceutical Grade
Product Categories: Amines;Heterocycles;Intermediates & Fine
Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.
What is Tetracaine HCL Powder?
Tetracaine HCl Powder is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Tetracaine HCl Powder Usage
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
1. It is used in ophthalmology and otolaryngology.
2. It can be used in epidural block, subarachnoid block and nerve conduction block.
This product is a long-acting ester local anesthetic. Its characteristics are: strong penetration of mucous membrane, suitable for surface anesthesia, no vasoconstriction, mydriatic dilation, corneal damage and other adverse reactions after eye drop, commonly used in ophthalmology. Local anesthesia and toxicity are about 10 times greater than procaine. After injection, the anesthesia was slow (about 10 minutes), and the metabolism was slow after absorption. The local anesthesia lasted for 3 ij, h, – J. About. It is mainly used for the surface anesthesia of the mucous membrane of eyes, nose and throat, but seldom for conduction anesthesia and epidural anesthesia. Because of its toxicity, it is not generally used for infiltration anesthesia.
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