Table of Contents
Quercetin Powder Briefing
Quercetin is extracted from the Sophora flavescens Ait. Quercetin is a potent antioxidant and has anti-inflammatory activity, protecting cellular structures and blood vessels from the damaging effects of free radicals. It improves blood vessel strength. Quercetin inhibits the activity of catechol-O-methyltransferase that breaks down the neurotransmitter norepinephrine. This effect may lead to elevated levels of norepinephrine and an increase in energy expenditure and fat oxidation. It also means quercetin acts as an antihistamine leading to relief of allergies and asthma. As an antioxidant, it reduces LDL cholesterol and offers protection from heart disease. Quercetin blocks an enzyme that leads to accumulation of sorbitol, which has been linked to nerve, eye, and kidney damage in diabetics.
Product Name:Quercetin
CAS:117-39-5
MF:C15H10O7
MW:302.24
EINECS:204-187-1
Mol File:117-39-5.mol
Melting point:314-317°C
Boiling point:363.28°C (rough estimate)
Density 1.3616 (rough estimate)
refractive index 1.4790 (estimate)
storage temp. Store at 0-5°C
pka6.31±0.40(Predicted)
form solid
Water Solubility <0.1 g/100 mL at 21 ºC
Quercetin is commonly used as a expectorant drug in clinical medicine in China. This product has various kinds of pharmacological functions such as having a good expectorant, cough effect, also having certain anti-asthma effect, and having further effects of lowering blood pressure, enhancing capillary resistance, reducing capillary fragility, reducing blood fat, expansion of coronary artery, increasing coronary blood flow.
Clinically, quercetin is mainly used for treating clinical bronchitis and phlegmatic inflammation. It also has adjuvant therapy effect on coronary artery disease and high blood pressure. FDA may have some kinds of adverse reactions such as dry mouth, dizziness, and burning sensation in stomach area which may disappear after treatment.
Quercetin is widely distributed in angiosperms such as Threevein Astere, Golden Saxifrage, berchemia lineata, gold, rhododendron dauricum, seguin loquat, purple rhododendron, Rhododendron micranthum, Japanese Ardisia Herb and Apocynum. It is a kind of aglycon which mainly combines with carbohydrate to be in the form of glycosides, such as quercetin, rutin, hyperoside.
Uses1. It can be used as a kind of antioxidant which is mainly used for oil, drinks, cold drinks, meat processing products.
2. It has good effects of expectorant, anti-cough, anti-asthma and can be used for treating chronic bronchitis as well as for adjuvant therapy of coronary heart disease and high blood pressure.
3. It can also be used as analytical standards
COA of Quercetin Powder
Items | Standards | Results |
Physical Analysis | ||
Description | Light Yellow Fine Powder | Complies |
Assay | Quercetin 95% (HPLC) | 95.26% |
Mesh Size | 100 % pass 80 mesh | Complies |
| Ash | ≤ 5.0% | 2.85% |
Loss on Drying | ≤ 5.0% | 2.82% |
| Chemical Analysis | ||
| Heavy Metal | ≤ 10.0 mg/kg | Complies |
| Pb | ≤ 2.0 mg/kg | Complies |
| As | ≤ 1.0 mg/kg | Complies |
| Hg | ≤ 0.1 mg/kg | Complies |
| Microbiological Analysis | ||
| Residue of Pesticide | Negative | Negative |
| Total Plate Count | ≤ 1000cfu/g | Complies |
| Yeast&Mold | ≤ 100cfu/g | Complies |
| E.coil | Negative | Negative |
| Salmonella | Negative | Negative |
Function of Quercetin Powder
1. Expel phlegm and arrest coughing, it can also be used as anti-asthmatic;
2. Quercetin has anticancer activity, inhibits PI3kinase activity and slightly inhibits PIP Kinase activity; reduces cancer cell growth via type II estrogen receptors;
3. Inhibit histamine release from basophils and mast cells;
4. Control the spread of certain viruses within the body;
5. Quercetin may also be beneficial in the treatment of dysentery, gout, and psoriasis.
Application of Quercetin Powder
1. Applied in pharmaceutical industry: Some medicine with bromelain like throat tablet can diminish inflammation, facilitate digestion and improve immunological competence.So it can be applied in examination, treatment of gynecopathy, glaucoma and inset bitten.
2. Applied in food industry: It can be applied in hydrolyzing protein of plants and animals, so it can be used in the meat tenderizer,wine clarifier,stabilizer of noodle,health foods and soy sauce brewing etc. It can also improve the nutritional value.
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