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YK-11 Powder
YK11 Powder– a strong myostatin inhibitor. YK11 works through the androgen receptor.
YK-11 is a SARM that acts as a gene-specific agonist of the androgen receptor (AR) in MDA-MB 453 cells. YK-11 works on a variety of different anabolic pathways. YK-11 has shown greater anabolic activity in vitro in C2C12 myoblasts than DHT [1, 2]. YK11 promoted a cascade of muscle growth and key myogenic regulatory factors in skeletal muscle tissue such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5), to a significantly greater extent than DHT. This can in part explain why YK11 exerts its selective modulation of the AR. Unlike testosterone and most other androgen receptor mediated anabolic agents, YK-11 is orally bioavailable so it does not require injection for proper absorption. At this time YK-11 is for laboratory research use only and the side effects are not fully known.
What really sets YK-11 apart is that a key component of its anabolic activity is modulated via expression of follistatin. They discovered this by co-administering anti-follistatin antibodies with YK11 to measure the difference in effects [2]. Follistatin has been shown to promote insulin-stimulated glucose and amino acid uptake into skeletal muscle cells, improving insulin sensitivity directly and increasing skeletal muscle mass [3]. Follistatin proteins also block inhibitory ligands from binding to Transforming Growth Factor-ß [4].
Perhaps the most alluring effect of follistatin is binding and neutralizing of catabolic proteins Activin A, Activin B, and Myostatin. Unfortunately follistatin proteins themselves undergo rapid proteolysis and have limited bioavailability and half-life even when injected directly into a wasting muscle. YK-11 however stimulates the body to produce more follistatin proteins systemically and locally which may circumvent this shortfall of direct follistatin administration and promote muscle growth [2, 4].
YK11 Powder Benefits And Side Effects
The effect from taking YK-11: The biggest benefit of YK-11 before and after results is the fact that it can change the body’s ability to generate muscle, increasing the amount of muscle which can be added. This occurs because YK-11 inhibits the production of myostatin, a compound which reduces muscle growth. Without the myostatin impairing the muscle’s ability to grow, the body is able to add lean tissue much more easily. The effect on muscular growth is so profound that the effect of YK-11 can be said to be comparable to testosterone, far exceeding the more limited androgenic effect that other modulators produce. In addition to these very powerful muscle-building effects, YK-11 can deliver the other benefits such as fat loss, improving strength and increasing the ability to recover more quickly.
How it works: YK-11 attaches itself to an androgen receptor. This prompts muscle cells to produce more anabolic factors that in turn leads to increased muscle growth. Unlike most modulators that come with limited androgenic effects, this compound performs much better. In a past study, the effect of this compound on muscle cells was proven to be much higher. It was found that the muscle cells produced more anabolic compounds when exposed to 500 nmol of this compound than when exposed to testosterone.
- Intake: Due to its half-life, it is suggested to space your dosing with meals, however you can take all at once
- Suggested Cycle: 12-16 weeks is optimal
- PCT: A full PCT is required to make sure you return to a healthy hormone balance.
Side effects: Based on first and logs findings, there are not any adverse effects noticed at all. YK11 has the ability to increase aggression but at the suggested dosage this should not be an issue.
WARNING: This is a research chemical only and is not intended for human consumption.
Data on our YK-11 Powder for sale
CAS Number: 1370003-76-1
Formula: C25H34O6
Molar Mass: 430.541 g/mol
Class: Myostatin Inhibitor, Selective Androgen Receptor Modulator
Experimental Application: Muscle tissue growth, Myostatin inhibition
Storage: Store in a cool dry place away from direct sunlight to maximize shelf life.
- Foil Pouch with UV resistance to minimize degradation.
- Minimum 98% pure.
- 1,050 Milligrams YK-11 per pouch.
- Measuring tools not included.
This preparation is for laboratory research purposes only and is not approved by the FDA for human consumption. YK-11 IS NOT A DIETARY OR SPORTS SUPPLEMENT.
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